Nine genes/proteins of interest (CXCL12, ENPP2, FBLN5, FGF2, LYVE1, PDGFRB, SERPINF1, TIMP2, TIMP3) were then selected from analysed datasets based on the following criteria: (a) the significant difference (adjusted p < 0.01) in gene expression between tumour and tumour-adjacent tissue was more than 3-fold, and (b) the significant difference in protein levels between tumour and adjacent tissues was more than 2-fold. The gene discussed is LYVE1; the disease is neoplasm.