In this study, the enrolment of patients with iCCA who were subjected to hepatic resection allowed them to assess the expression levels of somatostatin receptor 2 (SSTR2) and Bcl2 proteins to differentiate between perihilar (large bile duct) and peripheral (small bile duct) carcinogenesis in iCCA patients based on the expression levels of these two proteins. The gene discussed is BCL2; the disease is infantile convulsions and choreoathetosis.