sFRP4 expression was then investigated in iPSC, iPSC-GBM, iPSC-GSCs, iPSC-derived sFRP4 overexpressed glioblastoma cells and was found to be upregulated only in iPSC-derived sFRP4 overexpressed glioblastoma cells as confirmed by qPCR (Figure 6D). This evidence concerns the gene SFRP4 and glioblastoma.