Furthermore, in appendiceal cancers, mutations in the CTNNA1 gene are occasionally found in appendiceal goblet cell adenocarcinomas, and mutations in CTNNB1 are found in mucinous neoplasms of the appendix [7], low and high-grade appendiceal mucinous neoplasms, and appendiceal goblet cell adenocarcinomas [10,178]. This evidence concerns the gene CTNNB1 and goblet cell carcinoma.