APC and mucinous adenocarcinoma of the appendix: Mutations in the APC gene inhibit its function and are generally associated with cancers of the digestive tract, such as stomach, colon/colorectal [101,102], and some appendiceal cancers, such as low-grade appendiceal mucinous neoplasms, appendiceal adenocarcinomas [16,33,85], mucinous adenocarcinomas of the appendix, and appendiceal goblet cell adenocarcinoma [30].