Thus, 13 genes, KRAS, HRAS, NRAS, BRAF, EGFR, ERBB2, ERBB4, MET, FGFR13, KIT/cKIT, MYC/cMYC, and PLCG2, are part of the RAS–RAF–MEK–ERK signaling pathway, which in cancer stimulates proliferation and angiogenesis. This evidence concerns the gene RAF1 and cancer.