It encodes the serine/threonine kinase BRAF (766 amino acids; 84,437 Da) and frequently undergoes the missense mutation Val600Glu, which contributes to its activation and being associated with cardiofaciocutaneous, Noonan, and Costello syndromes, as well as with several cancers, including non-Hodgkin’s lymphoma, colorectal cancer, thyroid carcinoma, non-small-cell lung carcinoma, hairy cell leukemia, and adenocarcinoma of the lung [44]. Here, BRAF is linked to cancer.