Mutations in the MYC/c-MYC gene, which presumably have a stimulatory effect on its function, are also reported in less than 10% of cases of appendiceal goblet cell adenocarcinoma and mucinous/non-mucinous adenocarcinoma of the appendix [62,63], being a secondary mutation in appendiceal cancers. The gene discussed is MYC; the disease is goblet cell carcinoma.