Thus, mutations in the TP53 and APC genes are present in 27.3% and ~8% of appendiceal cancers, 75% and 75.9% of colorectal cancers, 58.4% and 7.8% of small bowel cancers, and 58.4% and 26.8% of gastric cancers. The gene discussed is TP53; the disease is gastric cancer.