Occasional exceptions can be found; for example, all 13 tRNA-Glu-TTC genes are active in one particular metastasis (M_013, Figure 7C), but this anomaly does not reflect the general hyperacetylation of tRNA loci in this sample, as only three out of nine tRNA-iMet-CAT genes are active in the same cancer (Figure 4C). Here, CAT is linked to cancer.