To validate these findings and to better understand the context in which constitutive Wnt signaling deregulates ECM genes, we performed a comparative analysis using another human adrenocortical tumor dataset annotated with the nuclear CTNNB1 status of each sample [14] and a mouse model of adrenal-specific β-Catenin GOF [36]. The gene discussed is CTNNB1; the disease is adrenal cortex neoplasm.