Tn and STn antigens, categorized as pan-carcinoma antigens, are truncated O-GalNAc or mucin-type O-glycans and associated with poor prognosis and cancer progression such as early carcinogenesis, progression, metastasis by suppression of immunosurveillance [34,35,36,37,38,39,40,41,42]. The gene discussed is MUC5AC; the disease is carcinoma.