MUC1 and familial pancreatic carcinoma: Furthermore, 5E5, one of the anti-Tn mAb that specifically recognizes Tn-carrying MUC1 (Tn+MUC1) [76], was employed on chimeric antigen receptor T-cell (CART), and demonstrated specific cytotoxicity to leukemic and pancreatic cancers with Tn+MUC1 expression using an in vivo xenografted mouse model [107].