Other markers and signs of type 2 inflammation were also significantly lower in T2 low patients, including maximal total IgE [24 (10, 77) vs. 222 (53, 427) kU/l, p < 0.01 in T2low300 vs. non-T2 low300] and nasal polyps that were absent in T2 low patients vs. observed in 10–14% of non-T2low patients. This evidence concerns the gene IGHE and Nasal polyposis.