GAPDH and myopia: In a mouse model of myopia induced by the wearing of a negative lens on one eye, we observed high levels of TGM-2 protein staining in the sclera (Figure 1A) and elevated TGM-2 transcription levels (Figure 1B) and protein levels (Figure 1C) in myopic sclera compared to the control sclera (normalized to the GAPDH).