TRPM2 and myalgic encephalomeyelitis/chronic fatigue syndrome: Quantification of TRPM7 surface expression is of interest to determine whether there is a relative abundance of TRPM7 to compensate for impaired TRPM7 ion channel stability, or secondary to the Ca2+ signalling dysregulation present in the NK cells of ME/CFS patients compared to HCs as reported for TRPM2 [22].