CXCL1 and obesity due to melanocortin 4 receptor deficiency: Interestingly, several of these chemokines were shown to promote the recruitment of other immune cells besides macrophages, such as neutrophils (as for CXCL1 and IL-8) [80] and Th1 (pro-inflammatory) cells (as for CCL5 and CXCL-10/IP-10) [81], that also infiltrate and derange adipose tissue in response to obesity [81,82].