Nevertheless, in the present study, PKD1 mutations (OR, 1.87; 95% CI, 1.11–3.16; p = 0.020) and an HtTKV ≥ 750 mL (OR, 1.67; 95% CI, 1.06–2.63; p = 0.029) were shown to be independent risk factors for ADPKD. The gene discussed is PKD1; the disease is autosomal dominant polycystic kidney disease.