Here, we will expand on four of the distinct subtypes of pediatric ependymomas; supratentorial ependymoma ZFTA fusion-positive, supratentorial ependymoma YAP1 fusion-positive, posterior fossa group A (PFA) ependymoma, and posterior fossa group B (PFB) ependymoma. This evidence concerns the gene YAP1 and supratentorial ependymoma.