EGFR and neoplasm: A previous study by Takano et al. reported that lesions with the wild-type EGFR mutation were located further away from the brain surface with a tumor depth of 15.0 mm (range: 10.0–20.7 mm) than the L858R EGFR lesions with tumor depth of 13.7 mm (range: 8.6–21.9 mm) [8].