Regarding the possible contribution of analyzing the number of TA repeats in the UGT1A1 promoter as another screening method to identify newborns, especially females, at risk for high NHB, it seems that the interaction with G6PD deficiency and significant neonatal jaundice is more complex, and requires further study and analysis before it can be recommended as a screening test for newborns. This evidence concerns the gene UGT1A1 and G6PD deficiency.