A similar trend in accelerated epigenetic aging could be observed in post-mortem brains of PSP patients compared to controls with both DNAmClockMulti and DNAmClockCortical; however, for the FTD subtypes, only the GRN mutation carriers (FTLD-TDPA) showed a consistent trend towards epigenetic age acceleration. Here, GRN is linked to supranuclear palsy, progressive, 1.