Tian et al. studied the effects of mdivi-1 (a Drp1 inhibitor) and P110 (a competitive peptide inhibitor of the Drp1–Fis1 interaction) on mitochondrial morphology, mitochondrial membrane potential and RV function before and after two cycles of ischemia reperfusion injury challenge (RV-IR) (Figure 7). The gene discussed is DNM1L; the disease is ischemia.