In sALS fibroblasts, we also found increased expression of the PAX8 antisense RNA1 (PAX8-AS1), a long non-coding RNA that is linked to cell cycle control and metabolic processes previously reported to be associated with different neurodegenerative diseases, including Parkinson’s disease and Huntington’s disease [94,95]. The gene discussed is PAX8; the disease is neurodegenerative disease.