Finally, a study performed in 641 Italian MS patients and 558 HC showed a protective role against MS risk for the VDR TaqI T allele-HLA-DRB1*15+ haplotype (p = 9.5 × 10−5; OR = 2.52; 95% CI = 1.56–4.06) and, on the contrary, an increased risk of developing MS associated with the -DRB1*15-VDR TaqI C haplotype. Here, HLA-DRB1 is linked to myeloid sarcoma.