NPC1 and Doyne honeycomb retinal dystrophy: There were also five proteins that were found to be dysregulated exclusively in DHD (i.e., Colipase, NAD(P)H-hydrate epimerase, cystic fibrosis transmembrane conductance regulator, Heat shock 70 kDa protein 1, and Chymotrypsinogen 2), and only four in CHD (i.e., hemoglobin subunit alpha, NPC intracellular cholesterol transporter 2, Actin, cytoplasmic 1, and lysozyme C, milk isozyme) as compared to the HD group.