According to preclinical studies, in men with prostate cancer, the administration of 8 ounces of pomegranate juice by mouth daily (Wonderful variety, equivalent to 570 mg total polyphenol gallic acid equivalents daily) slowed down the blood increment of prostate-specific antigen (PSA), a well-known marker of cancer progression [169,170]. The gene discussed is KLK3; the disease is prostate cancer.