LMNB1 expression was downregulated in AMD cybrids with PU-91 (P) (0.44-fold ± 0.06, p-value = 0.001), quercetin (Q) (0.57-fold ±0.14, p-value = 0.021), and in combination (P+Q) (0.37-fold ± 0.39, p-value = 0.002) treatment (Figure 8a). The gene discussed is LMNB1; the disease is age-related macular degeneration.