Our results show that while SOD2 expression decreases with PU-91 (P) treatment in Glc cybrids (0.63-fold ± 0.06, p-value = 0.02), it increases with the combination (P+Q) treatment in AMD cybrids (2.58-fold ± 0.45, p-value = 0.031) (Figure 5a). This evidence concerns the gene SOD2 and age-related macular degeneration.