Other effects include increased phosphorylated form of acetyl-CoA carboxylase (ACC) and decreased ACC, FA synthase, and activity of stearoyl-CoA desaturase (SCD) (inhibition markers of new hepatic lipogenesis) [143], further supporting the idea that physical exercise slows the progression of NAFLD by restoring normal mitochondrial biogenesis. Here, SCD is linked to metabolic dysfunction-associated steatotic liver disease.