CUX1 and schizophrenia: Exposure to 10 μM clozapine for 24 h led to significant increase in dendritic spine and synaptic puncta density (Fig. 3G) in CUX1-positive cortical neurons from schizophrenia iPSC lines, partially rescuing the cell type-specific deficits that we had described above in schizophrenia (Fig. 1C,F).