The iron deficiency-induced RNA-binding protein tristetraprolin (TTP) regulates gene expression by promoting the degradation of target mRNAs, including respiratory chain subunits encoding Fe/S clusters, such as NADH:ubiquinone oxidoreductase core subunit S1 (NDUFS1) in complex I and Ubiquinol cytochrome c reductase (UQCRFS1) in complex III [62]. This evidence concerns the gene NDUFS1 and nutritional disorder.