The results showed that the serum level of IL-33 was positively correlated with tumor stage (SMD = 0.936, 95% CI = 0.555–1.317, p < 0.000) and vascular invasion (SMD = 0.601, 95% CI = 0.387–0.815, p < 0.000), which was consistent with the results of the IL-33 tissue level. This evidence concerns the gene IL33 and neoplasm.