CEACAM5 and colorectal carcinoma: CTCs ≥ 11.85FU/3ml (OR = 1.090, 95%CI: 1.029 ~ 1.155), CEA ≥ 4.87ng/ml (OR = 1.007, 95%CI: 1.003 ~ 1.010), CA125 ≥ 19.90U/ml (OR = 1.004, 95%CI: 1.000 ~ 1.008), CA199 ≥ 26.55U/ml (OR = 1.002, 95%CI: 1.001 ~ 1.002) were independent influencing factors of distant CRC metastasis (all P < 0.05), as shown in Table 2.