Other treatment-related Grade 3 AEs included immune-related encephalitis, diarrhea, fatigue, aspartate aminotransferase/alanine aminotransferase/gamma-glutamyltransferase increase, blood alkaline phosphatase increase, abdominal distension, cutaneous rash (n = 1 each), and cholestasis (n = 2) that resolved or were resolving at the time of data cutoff (Table 2). The gene discussed is GPT; the disease is cholestasis.