NFKB1 and cancer: Increasing the expression of the pro-inflammatory transcription factor ‘nuclear factor kappa-light-chain-enhancer of activated B-cells’ (NF-κB), which regulates the expression of inflammatory and cytoprotective genes, inhibiting the cellular tumor antigen p53 (p53) and thus inducing cell survival, which is a significant obstacle to the treatment of cancer patients [7–10] are further key examples.