An interesting study identified circulating tumor microemboli (CTMs) and three subpopulations of CTCs, namely, E-CTCs, M-CTCs, and E/M-CTCs based on the expression of epithelial cell adhesion molecule (EpCAM), the mesenchymal cell marker vimentin, or both EpCAM and vimentin respectively from blood samples of 126 CRC patients. The gene discussed is VIM; the disease is colorectal carcinoma.