The third patient had a history of papillary thyroid carcinoma (PaedCan16) and was found to carry a pathogenic PALB2 variant (c.72del, p.(Arg26Glyfs*7)) as well as a pathogenic deletion of several exons of DICER1 (Ex1-7del, size 1.11 Mb), both inherited from her mother. The gene discussed is PALB2; the disease is thyroid gland papillary carcinoma.