IL-6 was not significantly different between patients with AECOPD and control patients (AECOPD inpatients: 7.2 ± 12.9; GOLD 1 and 2 Stable COPD controls: 5.8 ± 8.2; GOLD 3 and 4 Stable COPD controls: 3.2 ± 2.4; p = 0.787). This evidence concerns the gene IL6 and chronic obstructive pulmonary disease.