Intriguingly, multivariate Cox regression analysis identified PARP10 as an independent factor in AML prognosis for both OS and EFS after adjusting for age (<60 vs. >60), WBC count (≥30 vs. <30 × 109/L), FLT3 and TP53 statuses (wildtype vs. mutant), and transplant status (yes vs. no). The gene discussed is TP53; the disease is acute myeloid leukemia.