To further explore the mechanism of PARP10 in AML, we performed co-expression network analysis using RNA sequencing data from the 173 AML patients taken from the cBioPortal database [21] and found 558 positively co-expressed genes (r > 0.5; P < 0.05) and 94 negatively co-expressed genes (r < −0.5; P < 0.05) (Supplementary Table 1). Here, PARP10 is linked to acute myeloid leukemia.