Recently, JRTs with GI polyps have been proven to harbor an identical germline variant in the adenomatous polyposis coli (APC) gene c.[462_463delinsTT] (GenBank accession numbers: LC598892.1–LC598902.1 and LC600201.1–LC600209.1) in the heterozygous state, thus making this disease an autosomal dominant hereditary disorder [7]. The gene discussed is APC; the disease is gastrointestinal polyp.