INS and diabetes mellitus: However, decreased pancreatic β-cell secretion is relative and not absolute, which is confirmed on one hand by the insulin values, which on the 10th day after the induction of diabetes are comparable to those of the controls (Table 2), and on the other hand by the histological findings, which show areas in the pancreas with well-preserved endocrine and exocrine parts of its parenchyma and others with destruction of the islets of Langerhans (Figure 7b,c).