S100A12 and pancreatitis: Within this study, serum alpha1-proteinase inhibitor (α1PI; a marker of the systemic response to circulating proteases, which presumably have been released from the pancreas) and serum calprotectin and S100A12 (markers of systemic inflammation presumed to reflect an exaggerated local inflammatory response in the pancreas) were measured in 35 Miniature Schnauzers diagnosed with either a typical or an atypical presentation of pancreatitis assumed to reflect varying clinical severities.