In HCC HepG2 cells PRAMEF 14, SLAMF 9, TTC-36, LECT2, and PDLIM4 genes were upregulated after MC-LR treatment, whereas CYN exposure downregulated PRAMEF14, GPR52, CAPZA3, LECT2, CGS, TPRM1, TEK, PDLIM2, and TFF1 in HepG2 cells (Figure 8C, left and right panels). This evidence concerns the gene TEK and hepatocellular carcinoma.