IFNG and toxoplasmosis: Among the host cell responses, cell-mediated immune responses through the production of the proinflammatory cytokine, e.g., interleukin 12 (IL-12), IL-1β, and IFN-γ, by macrophages and dendritic cells (DCs) are considered as the main modulating inflammatory pathways for controlling of parasite burden and disease in toxoplasmosis [6].