GSTM1 and anemia: The mean Hb increase after 2 months was the same in all groups (1.4 g/dL), but side effects were significantly greater in the higher dosages.[10] To minimize side effects and maximize the amount of elemental iron absorbed, a single daily dose or a slightly greater alternate–day dose is generally thought to be the ideal dosing regimen.[10,11,15] These findings should be interpreted cautiously due to the small sample size, the short duration of iron therapy, and the patients’ absence of anemia.