TGFB1 and Myocardial fibrosis: Treatment with pterostilbene has been shown to inhibit oxidative stress-mediated Pitx2c/miR-15b pathway and suppression of p-p53-dependent TGF-β1/Smads/CTGF activation, resulting in the alleviation of high-fructose-induced myocardial fibrosis [177].