To reduce the risk of neonatal death, respiratory distress syndrome, cerebrovascular hemorrhage, necrotizing enterocolitis, respiratory support and intensive care unit (ICU) admission, administration of corticosteroids were recommended in cases of severe hypertension, and preeclampsia with severe features before 34 weeks (FSH, NICE, NZ and SA). This evidence concerns the gene BRD2 and newborn respiratory distress syndrome.