The explanations of these discordances are contradictory and based on: (i) different metastasis environment with a loss of expression of PSMA that can occur in less than 10% of primary or metastatic prostate tumours [24]; (ii) tumour progression between scans in cases of a wide time interval [9]; and (iii) unspecific inflammation that promotes choline uptake in lymph nodes and can explain additionally choline-positive lymph nodes [25]. The gene discussed is FOLH1; the disease is neoplasm.