The expression levels of PODNL1 were found significantly higher in tumor tissues in 15 types of cancers including BLCA, breast-invasive carcinoma (BRCA), cholangiocarcinoma (CHOL), colon adenocarcinoma (COAD), esophageal carcinoma (ESCA), HNSC, KIRC, lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSC), OV, pancreatic adenocarcinoma (PAAD), pheochromocytoma and paraganglioma (PCPG), rectum adenocarcinoma (READ), sarcoma (SARC), and stomach adenocarcinoma (STAD), compared with in normal tissue samples. This evidence concerns the gene PODNL1 and squamous cell lung carcinoma.