Genes impacting mitochondrial function include 31 of 37 in mitochondrial DNA and nuclear genes encoding mitochondrial proteins, including ten EDS-related (NDUFA-11/S3, OPA1, TYMP, etc.)and three COVID-19-related (STAT2, TLR3, NDUFAF7) genes. The gene discussed is NDUFAF7; the disease is COVID-19.