In addition, Ährlund-Richter et al. [35] showed that MUC6 and MUC16 were mutated in over 30% of primary HPV-positive tonsillar squamous cell carcinoma (TSCC) and base of tongue squamous cell carcinoma (BOTSCC) with and without recurrence. Here, MUC16 is linked to tonsillar squamous cell carcinoma.