MiRNAs in melanoma are involved in the regulation of several key signaling pathways, including the MAPK pathway (e.g., miR-let-7a, miR-137, miR-184, miR-211), PI3K/AKT pathway (e.g., miR-17-5p, miR-126, miR-155), and Wnt/β-catenin pathway (e.g., miR-26a, miR-26b, miR-146a). The gene discussed is AKT1; the disease is melanoma.