CRP and rheumatoid arthritis: It has been reported that oral application of 1 g of resveratrol co-administered to RA patients with their conventional drug improved the disease induced symptoms by reducing clinical markers (i.e., the 28-joint count for swelling and tenderness) as well as serum levels of certain biochemical markers (i.e., C-reactive protein, TNF-alpha, and IL-6) [101].