When stratified by genetic polymorphisms of FUT2, LRAU appeared to confer a comparatively greater risk for early‐onset adenomas among participants with rs281377 TT genotype (OR = 1.10, 95% CI = 0.79‐1.52, P = .587, for CC genotype; OR = 1.75, 95% CI = 1.16‐2.64, P = .008, for TT genotype; Pinteraction = .089). Here, FUT2 is linked to adenoma.