In order to elucidate the molecular mechanisms underlying the ameliorative effects of FGF10 on AD‐like symptoms and pathologies, we conducted an analysis of the phosphorylation and total levels of FGFR1, FGFR2, FGFR3, Fibroblast Growth Factor Receptor Substrate 2 (FRS2), and AKT. The gene discussed is FRS2; the disease is Alzheimer disease.