Our findings indicate that intranasal administration of FGF10 and tail vein injection of FGF10 can improve the expression of soluble and insoluble forms of Aβ1–42 and Aβ1–40 in the hippocampus and cortex of 3xTg mice 3xTg‐AD mice (Figure S5i,j,q,r). Here, FGF10 is linked to Alzheimer disease.