IGF2BP1 and precursor B-cell acute lymphoblastic leukemia: The Gene Ontology enrichment analysis of upregulated genes in the same data set (~1,300 genes) indicates that IGF2BP1 knockdown in ALDH-enriched B-ALL 697 (EU3) cell line induces type I interferon, interferon-γ-mediated, and defense response to virus pathways (Figure 1A).