Macrophages and their precursors, monocytes, marked by IBA1 showed higher tumor infiltration both at week 1 and 4 post-tumor cell implantation in the ETBF group, while higher IBA1-positive cells were also observed in adjacent normal breast of ETBF-infected mice (Supplementary Figures S7A, B). This evidence concerns the gene AIF1 and neoplasm.